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Figure 10


Fig. 10. Sox9flox/-; AMH-Cretg/+ male mice develop normal testes at E18.5. (A-F) Sox9flox/+; AMH-Cretg/+ male mice were crossed with Sox9flox/flox; Zp3-Cretg/+ female mice to obtain Sox9flox/-; AMH-Cretg/+ embryos. Hematoxylin and Eosin staining showing normal histology of Sox9flox/-; AMH-Cretg/+ testes (D) when compared with control testes of the same age (A). SOX9 was totally deleted in Sertoli cells of mutant testes (E). However, the expression of AMH and β-catenin in Sertoli cells was unaffected upon SOX9 deletion (E,F). Scale bar: 20 µm.





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