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Figure 7


Fig. 7. Similar functions of tip cells in the tracheal system and in the developing vasculature. (A) A terminal cell (TC) and a fusion cell (FC) of the Drosophila tracheal system, which form the tip of a dorsal branch and express GFP::Actin (stage 15 of embryonic development). Note the presence of filopodial extensions in the TC and the FC, and their absence in stalk cells (SCs). (B) An endothelial tip cell, expressing GFP in a developing intersegmental vessel of an early zebrafish embryo (image courtesy of Y. Blum). (C) Isolectin B4-labelled endothelial tip cell (green) at the leading front of the developing vasculature in the retina of a 5-day postnatal mouse. Nuclei are labelled with DAPI (blue; image courtesy of H. Gerhardt).





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