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Figure 4


Fig. 4. dmd-3 expression in the tail tip is regulated by lin-41, Wnt signaling and a positive-feedback loop. (A) dmd-3::YFP (fsIs3) expression in wild-type (i) and lin-41(bx42gf) (ii) mid-L4 males. The arrowhead in ii indicates the absence of dmd-3::YFP expression in hyp10 in lin-41(bx42) males. (B) dmd-3::YFP (fsIs3) expression in wild type (i) and lin-41(ma104lf) (ii) late L3 males. The arrow in ii highlights the precocious tail tip retraction in lin-41(ma104) males. (C) dmd-3::YFP expression in wild type (i-iii), lin-44(n1792) (iv-vi) and tlp-1(bx85) (vii-ix) L4 males of the indicated stages. (D) dmd-3::YFP (fsIs2) expression in wild type (i), dmd-3(ok1327) (ii), mab-3(e1240) (iii) and mab-3(e1240); dmd-3(ok1327) (iv) mid-L4 males. In A,C, the larval cuticle is shown with dashed lines. Dotted lines indicate the developing adult cuticle.





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