|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 8. Repression of projection neuron identity upon constitutive activation of
Notch. (A,B) Confocal projections of a control (A) and a
Tg(hs:Gal4); Tg(UAS-Nintra) double transgenic (B) embryo 48 hours
after a heat shock performed at 9 hours (B). Cells are labeled with HuC/D and
with FRet43. (C-E) Average numbers of Islet1+ cells (C), Tg(HuC:GFP)+
(D) and Tg(AANAT2:GFP)+ cells (E) at 48 hours in control and Tg(hs:Gal4);
Tg(UAS-Nintra) double transgenic embryos heat shocked at 9 or 24 hours. As the
constitutive expression of Notch intra impairs the formation (or the
migration) of the parapineal organ, which originates from the epiphysis
(Concha et al., 2003), we
counted the total numbers of Islet1+ in epiphysis and parapineal in the
control embryos. Scale bar: 16 µm. Error bars represent s.d.
*P<0.05; ***P<0.0005 using a
t-test.
|
