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Fig. 1. Alignment of the predicted amino acid sequence of LvNumb and Human Numb1
proteins. (A) Identical residues are denoted by an asterisk and
conserved by `.' or `:'. The four conserved domains are labeled. (B) A
molecular phylogeny of the Numb and Numb-like family members. Abbreviations:
Ce, C. elegans; Mm, mouse; Rn, rat; Hs, human; Tn, Tetraodon (puffer
fish); Dr, zebrafish; Xt, Xenopus tropocalis; Gg, chicken; Ci,
Ciona; Lv, Lytechinus; Dm, Drosophila.