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Fig. 5. Proliferation and development of non-hematopoietic tissues, including
the vascular system, are normal in c-Myc-deficient embryos. (A)
Immunohistochemical analysis of BrdU incorporation in control (left) and
c-Myc-deficient (right) embryos at E11.0. (B) PECAM (CD31) staining in
wholemounts (top) and histological sections (bottom) show normal development
of the vascular system in the embryo, the placenta and the YS of
Sox2Cre;c-mycflox/flox
embryos at E11.0.