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Figure 6


Fig. 6. Hematopoietic- and endothelial-specific elimination of c-Myc via Tie2Cre. (A) Phenotypes of control and Tie2Cre;c-mycflox/flox embryos and YS at E11.0. (B) Quantitative analysis of total CD45+ cells per E11.0 embryos (**P≤0.001). (C) FACS analysis showing the expression of the stem cell markers Kit (CD117) and AA4.1 (CD93) in CD45+ hematopoietic cells of control (left) and Tie2Cre;c-mycflox/flox (right) embryos at E11.0. Numbers represent percentages in the CD45+ population.





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