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Fig. 1. Mouse Cdx gene overexpresser (OE) constructs for preparation of
transgenic mice. The OE constructs (A-C) were derived as
modifications of Cdx/lacZ reporter constructs (D-F) previously
found to mimic expression of endogenous Cdx genes in early embryos
(Gaunt et al., 2003;
Gaunt et al., 2005).
(G-I) Cdx1, Cdx2 and Cdx4 genomic maps. Grey
boxes indicate Cdx exons; hatched boxes indicate lacZ/SV40polyA DNA;
K, KpnI; H, HindIII; R, EcoRI; Sp, SpeI;
Bg, BglII; S, SalI.