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Fig. 3. Temporal control of dFMRP expression by acute early RU486 treatment.
(A) Depiction of time line employed for early Drosophila
larval induction of dFMRP indicating points of dFMRP protein analyses.
(B) Representative western blot of first instar larval CNS probed for
dFMRP and 
-Tubulin. Samples were taken immediately after a 12-hour
treatment with RU486 as indicated. (C) Quantification of western blot
dFMRP levels. Individual band intensities were normalized to -Tubulin
and expressed as a percentage of the control. Bars indicate mean±s.e.m.
(D) Representative western blots of second and third instar larval CNS.
dFMRP levels progressively diminish and are minimally detectable 60 hours
post-treatment. (E) Quantification of dFMRP levels as a function of
age. Individual band intensities were normalized to -Tubulin and
expressed as a percentage of the control. Bars indicate mean±s.e.m.
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