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Figure 8


Fig. 8. Constitutive presynaptic dFMRP does not rescue dfmr1-null mEJC function defect. (A) Sample miniature excitatory junctional current (mEJC) traces from wandering third instar Drosophila larval NMJs showing 3 seconds of recording from control, dfmr1-null, GS+E, GS+R0.5 and GS+R2. Note the increased number of events in the dfmr1-null compared with the control, and the further increase upon dFMRP induction. (B) Quantification of mEJC peak amplitude. (C) Quantification of mEJC frequency. Bars indicate mean±s.e.m.; n=10 for each category. *P<0.05, **P<0.01, ***P<0.001.





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