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Fig. 6. Reduced expression of angiogenic factors in Cx43-deficient
uteri. (A) Uterine sections from Cx43fl/fl mice
on day 7 (a) and day 8 (b) and those from Cx43d/d mice on
day 7 (c) and day 8 (d) were subjected to immunohistochemical analysis using
anti-Vegf antibody. E, implanted embryo; M, the mesometrial region. (B)
qPCR analysis was performed to monitor angiopoetin 2 and angiopoetin 4 mRNA
expression in the uteri of Cx43fl/fl and
Cx43d/d mice on day 8 of pregnancy (n=3).