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Figure 6


Fig. 6. Mitochondrial volume and structure are abnormal in SdhA mutant R cell terminals. (A-E') Ultrastructural analysis of wild-type (A,A',D,D') or SdhA1110 mutant (B,B',C,C',E,E') R cell terminals in the lamina on the day of eclosion (A-C) or 5 days after eclosion (D,E). Asterisk marks a multilamellar body. (A',B',C',D',E') Schematic tracings of R cell terminals (black lines, R), lamina neurons (blue lines, L), and mitochondrial profiles within R cell terminals (magenta), or unidentifiable cells (gray). Insets show profiles of single mitochondria. Specialized glial invaginations called capitate projections are denoted (cp). Scale bar: 1 µm; in inset, 0.1 µm. (F) Quantification of mitochondrial area per terminal area in control (gray) and SdhA mutants (blue).





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