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Fig. 3. Meiotic defects in CTCF-depleted oocytes. Eggs having undergone GVBD
by 2 hours of culture were processed for diakinesis spreads. Eggs that have
undergone PBE by 16 hours of culture were processed for M2 spreads. Line 1 is
shown. Seven percent (3/42) of Tg eggs that have undergone PBE contained
roughly 20 bivalents. n=number of oocytes. Scale bar: 0.1 µm.