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Fig. 1. vHnf1 expression in the developing mouse liver.
(A-D) In situ hybridization identifying vHnf1 expression in
developing liver of sagittal (A,D) or transversal (B,C) sections of wild-type
(WT) mouse embryos at 8s (A), 20s (B) and 30s (C,D). (A) vHnf1
transcripts are visualized in the ventral hepatic endoderm (white arrow), in
the visceral endoderm (visc., black arrow) and at higher levels in the neural
tube (nt). (B) vHnf1 is strongly expressed in the liver bud (Li)
invading the adjacent septum transversum mesenchyme (stm). (C) vHnf1
is strongly expressed in the lung bud (Lu) and in the gall bladder (gb), but
is expressed at much lower levels in the migrating hepatoblast (hb). (D)
Strong vHnf1 expression is observed in the entire gut (g), ventral
and dorsal pancreas (vp, dp), gall bladder (gb), lung buds (Lu) and
hepatoblasts (hb). Axes: A, anterior; D, dorsal; V, ventral.