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Figure 1


Fig. 1. vHnf1 expression in the developing mouse liver. (A-D) In situ hybridization identifying vHnf1 expression in developing liver of sagittal (A,D) or transversal (B,C) sections of wild-type (WT) mouse embryos at 8s (A), 20s (B) and 30s (C,D). (A) vHnf1 transcripts are visualized in the ventral hepatic endoderm (white arrow), in the visceral endoderm (visc., black arrow) and at higher levels in the neural tube (nt). (B) vHnf1 is strongly expressed in the liver bud (Li) invading the adjacent septum transversum mesenchyme (stm). (C) vHnf1 is strongly expressed in the lung bud (Lu) and in the gall bladder (gb), but is expressed at much lower levels in the migrating hepatoblast (hb). (D) Strong vHnf1 expression is observed in the entire gut (g), ventral and dorsal pancreas (vp, dp), gall bladder (gb), lung buds (Lu) and hepatoblasts (hb). Axes: A, anterior; D, dorsal; V, ventral.





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