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Figure 7


Fig. 7. Area marker genes are shifted posteriorly by Fgf8 overexpression. (A) Steel is specifically expressed in the Th and cerebral peduncle in PTh (arrow). The border of dLGN and vLGN is distinguished by Steel expression (red arrow). The dorsal lateral geniculate nucleus (dLGN), mammilothalamic tract (MMT) and hippocampus (Hi). (B) The entire PTh is labeled by Gad67, and structures such as vLGN are easily distinguished (red arrow). (C) VP is specifically labeled by Cdh6. (D) Fgf8 electroporation shifts Steel expression posteriorly (arrowheads). The gap between the cerebral peduncle (arrow) and Steel-expressing border is expanded. (E) The region of Gad67 expression in PTh is enlarged in Fgf8-electroporated brain (arrow). However, it remains unclear which specific prethalamic nuclei are expanded. (F) Specific Cdh6 expression is shifted posteriorly and compressed in Fgf8 electroporated brain. Scale bar in D: 0.75 mm.





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