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Fig. 6. Dlx1-/-;6-/- and
Dlx2-/-;6-/- head skeleton
phenotypes. Head skeleton and skeletal elements of E18.5-P0 mice stained
with Alcian Blue (cartilage) and Alizarin Red (bone). (A-F) Lateral
views of the whole head. (G-L) Dentaries. (M-R) Skull base
views; the right half is a mirror image of the left half with individual
skeletal components highlighted by color. (S-X) Oblique lateral views
of the head after removing dentary. (Y-d) Middle ear ossicles,
ectotympanic and gonial. Note that os paradoxicum (OP) of
Dlx1-/-;6-/- and
Dlx2-/-;6-/- has been integrated into the skull
base (see Fig. S6E,F in the supplementary material), and thus excluded from c
and d. avp, alveolar process; BS, basisphenoid; E, eye; PT, pterygoid; for
remainder, see legends to Figs
4 and
5. *, duplicates
found in the mutants. Scale bars: 1 mm.