spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 3


Fig. 3. Proliferation and cell death in Cited2-/- lens. (A-C) Proliferation of the developing mouse lens at 10.5 dpc was examined by phosphorylated histone H3 immunostaining (green) and counterstained with DAPI (blue). No significant difference in proliferation was detected between Cited2+/+ littermate controls (A) (n=3) and Cited2-/- lens (B) (n=5); the data are summarized in C (P>0.05). (D-F) Cell death of the developing lens at 10.5 dpc was examined by the TUNEL assay. For counting cell number, sections were counterstained with DAPI to reveal nuclei (data not shown). Compared with Cited2+/+ littermate controls (D) (n=3), increased cell death was observed in Cited2-/- lens (E) (n=5); the data are summarized in F (P<0.01).





Right arrow Return to article