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Fig. 7. Loss of lines function in the DP results in transformation of
DP into PE fate. lines mutant clones generated at the second
instar and stained for peripodial, hinge and pouch markers. (B,D-F) FLP/FRT
and (A,C) MARCM clones; arrows point to magnified regions shown in right
insets. Arrowheads in C'-C'' and D'-D'' indicate planes
of z-sections shown in C'''-C'''' and D''',
respectively. Images in A-B,E-F are projections. lines mutant clones
occasionally overproliferated and protruded from the disc epithelium.
(A,B) DP markers Nub (A) and Vg (B) were lost in these clones.
The clone marked with an arrowhead in A,A' is below the Nub domain and
lost Nub expression. (C-D''') Reciprocally, the PE markers Ubx (C)
and Eya (D) were ectopically expressed in these clones. Ubx was detected only
in posterior DP clones. (C''',C'''',D''')
z-sections reveal basal extrusion of clones from the DP. (E)
Tsh and (F) Hth, which mark the PE, the notum and the hinge, were
ectopically expressed in these clones.
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