|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
| ||||||||||||||||||||
Files in this Data Supplement:
Fig. S1. Definition for coherence of cell migration. See details in Materials and methods.
Fig. S2. Quantification of the length of the posterior prechordal plate. Quantification is based on data in Fig. 1I-L and Fig. 6G-I. Statistically significant differences are indicated (#P<0.05 and ##P<0.005).
Fig. S3. Abrogation of Mil and Edg1 function modulates movements of the presumptive hypothalamus. (A-D) Uninjected WT embryo (A) and WT embryos injected with 4.3 ng mil-MO (B), 6.2 ng edg1-MO (C) or 4.3 ng mil-MO + 6.2 ng edg1-MO (D). The embryos were fixed at tailbud stage for in situ hybridisation with the markers dlx3 (for the anterior edge of the neural plate), pax2.1 (for the prospective mid-hind brain boundary) and nkx2.1 (for the presumptive hypothalamus). The position of the presumptive hypothalamus is highlighted by the dotted lines.
Fig. S4. Time-lapse analysis and tracking of cell movement in migrating prechordal plate progenitors. (A-L) WT embryos injected with 4.3 ng mil-MO (A-C), 125 pg p100CAAX (ca-PI3K) RNA (D-F), 250 pg dn-PI3K RNA (G-I) or 250 pg dn-PI3K RNA together with 4.3 ng mil-MO (J-L).
| ||||||||||||||||||||
