spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 3


Fig. 3. Mwh is an FH3-domain protein that localises more strongly proximally in cells. Adult (A-C) or pupal (E-G'') Drosophila wings. (A) mwh1 adult wing between veins 3 and 4, showing trichomes with characteristic multiple wing hair phenotype. (B) Wing expressing CG13913-IR under control of ptc-GAL4 between veins 3 and 4 showing a multiple wing hair phenotype. (C) mwh1 wing expressing EGFP-CG13913 from a P{w+, ActP-EGFP-CG13913} transgene showing rescue of the multiple wing hair phenotype. (D) Diagram of the CG13913 coding sequence, showing the extent of the Interpro GBD/FH3 (IPR014768) and FH3 (IPR010472) domains, and the point at which the inversion in mwh1 breaks the coding sequence (367, arrow). (E-E'') mwh1 clone in a 32-hour wing, labelled for Mwh (magenta), clonal marker (lacZ, green) and Fmi (blue). (F-F'') mwh1 clone in a 32.5-hour wing, labelled for Mwh (green) and actin (Ph, magenta). Arrowheads indicate trichomes in which Mwh does not colocalise strongly with actin bundles. (G-G'') mwh1 clone in 32.5-hour wing, labelled for Mwh (green) and {alpha}-tubulin (magenta). Arrowheads indicate trichomes in which Mwh does not colocalise with {alpha}-tubulin. Scale bars: 50 µm in A; 10 µm in G''.





Right arrow Return to article