spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 2


Fig. 2. Temporal and spatial pattern of expression of ephrin/Eph genes. (A-I) In situ hybridization for EphA4 (A,D,G), ephrin A5 (B,E,H) and ephrin B2 (C,F,I) in mouse embryos. (A-C) At E12.5, ephrin A5 and ephrin B2 are expressed in the ventricular zone (VZ), as well as in the presumptive striatum (Str, arrows in B,C), whereas EphA4 is expressed only weakly in the VZ (arrows in A). (D-F) At E14.5, ephrin A5 and ephrin B2 are expressed throughout the striatal mantle. EphA4 expression also starts to be detected, although mostly remains in the VZ. (G-I) At E16.5, the striatum is diffusely stained for both ephrin ligands and for EphA4. (J-O) In situ hybridization for EphA4 (J,M) and ephrin A5 (K,N) and ephrin B2 (L,O), at peri-natal stages. EphA4 receptor displays a matrix-like pattern of expression surrounding patches of negative expression (arrows in M), ephrin A5 is expressed in a progressively more restricted pattern, resulting in a distribution in patches (arrows in N), whereas ephrin B2 is expressed in a diffuse and progressively weaker pattern.





Right arrow Return to article