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Figure 1


Fig. 1. Programmed cell death of migrating germ cells in wild-type, p53 and out mutant embryos. Total numbers of PGCs in embryos between stages 10-14 were determined. In wild-type embryos, germ cell death was essentially complete by stage 12. In p53 and out embryos, germ cell death was disrupted. Similar numbers of PGCs were observed with a gradual loss of germ cells between stages 10 and 14. Error bars represent s.d.





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