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Figure 1


Fig. 1. Corin expression is confined to the DP. In situ hybridization to detect Corin transcripts (blue) in FVB mice. Corin is first detected when the dermal condensate segregates from surrounding dermis during the first (A, E15.5) and second (B, E16.5) waves of follicle formation. Follicles derived from the first, second and third waves of follicle formation are indicated. Throughout the growth phase of the hair cycle, Corin transcripts are expressed in the DP and not detected elsewhere in the skin. Samples from E17.5 (C) P0 (D,E), P3 (F) and P11 (G) mice are shown. The field enclosed by the red square in D is shown at higher magnification in E to reveal that Corin is expressed throughout the DP and not in the surrounding hair matrix.





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