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Figure 4


Fig. 4. Each Hox CP gene represses optix in its ventral, anterior ectodermal activity domain. Expression of optix (green) in (A) tsh- HoxCP, (B) tsh- Hox- Scr+, (C) tsh- Hox- Antp+, (D) tsh- Hox- Ubx+, (E) tsh- Hox- abdA+, (F) tsh- Hox- AbdB+, (G) Dfd, (H) lab. (A) Elav staining (red) highlights the ventral side. (B-F) The distribution of Hox proteins is in red. Arrows delimit the boundaries between optix expression and Hox domains. Scr+ (B) has one patch less (Lab segment) compared with A; Antp+ (C) presents only two (Lab and T1), Ubx+ (D) four (Lab to T3), abdA+ (E) five (Lab to A1) and AbdB+ (F) has eight (Lab to A4) ectopic patches of optix. (G) Loss of Dfd induces an ectopic optix patch in the maxillary segment (white arrow); arrowheads indicate the two normal domains of optix in the gnathal segments. (H) optix distribution is normal in lab (compare Fig. 2B). All panels are ventral aspects.





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