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Figure 1


Fig. 1. Temporal and spatial expression of fgfA and FGFR2 in sea urchin. (A,B) Northern blot analysis of fgfA and FGFR2 expression. (C) Scheme of early development of the sea urchin embryo describing morphogenesis of the skeleton. Spatial distribution of fgfA (D-M) and fgfr2 (N-W) transcripts during normal development analysed by in situ hybridization. Insets in E and M show the same embryo in a different focal plane. (N) Egg, (O) 16-cell stage, (P) 120-cell stage, (D,E) swimming blastula, (F,G,Q) mesenchyme blastula, (I,J,R,S) early gastrula, (K,T) late gastrula, (L,M,U,V) prisme/early pluteus (36 hours), (W) pluteus (48 hours). Ectodermal and mesodermal expression domains are indicated by arrows in K.





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