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Fig. 6. Overexpression of osr1 causes expansion of pronephric
progenitor number and a reduction in angioblast number. Control embryos
(A,C) and embryos injected with 100 pg of osr1 mRNA (B,D). (A)
Control expression of pax2a is expanded after injection of
osr1 mRNA (B), specifically in the mid-portion of the IM
(arrowhead, B), which is normally downregulated in the control embryos at the
13-somite stage (arrowhead, A). myoD is used as an internal control
for somite staging in these embryos (A,B). (C,D) Expression of
scl is lost in the anterior lateral plate mesoderm (arrowhead, D) in
the embryos injected with osr1 mRNA when compared with the uninjected
controls (arrowhead, C).
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