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Figure 2


Fig. 2. Genetically relocated Cdk2 loses its meiotic function. (A) Testes from P90 Cdk2+/+ (Aa), Cdk2-/- (Ab), Cdk2+/+ Cdk1+/Cdk2KI (Ac) and Cdk2-/- Cdk1+/Cdk2KI (Ad) mice. (B) Ovaries from P90 Cdk2+/+ (Ba), Cdk2-/- (Bb), Cdk2+/+ Cdk1+/Cdk2KI (Bc) and Cdk2-/- Cdk1+/Cdk2KI (Bd) mice. (C-F) H&E-stained testes sections from P90 Cdk2+/+ (C), Cdk2-/- (D), Cdk2+/+ Cdk1+/Cdk2KI (E) and Cdk2-/- Cdk1+/Cdk2KI (F) mice. (G,H) Testes sections, stained for β-galactosidase, from Cdk2+/+ Cdk1+/Cdk2KI (G) and Cdk2-/- Cdk1+/Cdk2KI (H) mice. (I-L) H&E-stained ovary sections from P90 Cdk2+/+ (I), Cdk2-/- (J), Cdk2+/+ Cdk1+/Cdk2KI (K) and Cdk2-/- Cdk1+/Cdk2KI (L) mice. Representative pictures are presented. Scale bars: 20 µm in C-F; 50 µm in G-L.





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