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Figure 3


Fig. 3. Knockin Cdk2 fails to function in meiosis. (A,B) H&E-stained testes sections from P10 Cdk2+/+ (Aa), Cdk2-/- (Ba), Cdk2+/+ Cdk1+/Cdk2KI (Ab) and Cdk2-/- Cdk1+/Cdk2KI (Bb) mice. Testes sections, stained for β-galactosidase, from P10 Cdk2+/+ Cdk1+/Cdk2KI (Ac) and Cdk2-/- Cdk1+/Cdk2KI (Bc) mice. Apoptotic testes sections from P10 Cdk2+/+ Cdk1+/Cdk2KI (Ad) and Cdk2-/- Cdk1+/Cdk2KI (Bd) mice. (C,D) H&E-stained testes sections from P20 Cdk2+/+ (Ca), Cdk2-/- (Da), Cdk2+/+ Cdk1+/Cdk2KI (Cb) and Cdk2-/- Cdk1+/Cdk2KI (Db) mice. Testes sections, stained for β-galactosidase, from P20 Cdk2+/+ Cdk1+/Cdk2KI (Cc) and Cdk2-/- Cdk1+/Cdk2KI (Dc) mice. Apoptotic testes sections from P20 Cdk2+/+ Cdk1+/Cdk2KI (Cd) and Cdk2-/- Cdk1+/Cdk2KI (Dd) mice. Scale bars: 40 µm, except 100 µm in Ad,Bd,Cd,Dd.





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