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Figure 5


Fig. 5. Otx2 overexpression does not affect the generation and identity of RN and OM neurons. (A-X) Immunohistochemistry performed on the intermediate mesencephalon of E12.5 and E18.5 tOtx2bov/+, En1Cre/+; tOtx2ov/+ and En1Cre/+; tOtx2ov/ov with Otx2 and Pitx3 (A,I,Q), AADC and Pou4f1 (B,J,R), Lmx1b and Isl1 (C,K,S), Pitx3 and Pou4f1 (D,L,T), Nurr1 and Lim1/2 (E,M,U), Pitx3 (F,N,V), Pou4f1 (G,O,W) and Isl1 (H,P,X). Abbreviations: OM, oculomotor nucleus; RN, red nucleus; VTA, ventral tegmental area.





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