spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 3


Fig. 3. Late degeneration of the Fz5-/- retina. (A,B) Semi-thin, plastic-embedded sections of (A) WT and (B) Fz5-/- mouse retinas at ~6 months of age stained with Toluidine Blue. In the Fz5-/- retina, there is a nearly complete loss of photoreceptor outer segments (OS), swelling of inner segments (IS), and cell and neuropil loss in the two plexiform and three nuclear layers (ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layer). (C) Fz5-/- retina and choroid at ~6 months of age showing extensive retinal folding and detachment. (D,F) High-magnification views from C, showing detachment and folding (D) and rosette formation (F). (E) High-magnification view of the upper right corner of D showing that the subretinal space is populated by macrophages (arrowheads).





Right arrow Return to article