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Figure 2


Fig. 2. The GATA4-FOG2 complex is essential for the activation of dimorphically expressed genes. (A-G,J-M) Whole-mount ISH was performed with Sprr2d (A-D), Foxl2 (E-G), Gng13 (J,K) and Sf1 (Nr5a1; L,M) RNA probes on XX gonads from wild-type, Gata4ki/ki and Fog2-/- E12.5-13.5 mouse embryos as indicated. (H,I) Immunofluorescent staining of frozen gonadal sections from Fog2+/- (control) or Fog2-/- embryos with an anti-FOXL2 antibody (red). Embryonic germ cells are detected by the anti-PECAM1 antibody (e.g. Yao et al., 2003) (green). Magnification: 200x.





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