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Fig. 1. Differential gene expression along the AP axis of E13.5 palatal
shelf. (A,E) Gradient Wnt5a expression is detected
in palatal mesenchyme, higher in the anterior (A), and lower in the posterior
(E) domain. (B,F) Fz4 expression is detected in the
anterior palate (B), but not in the posterior region (F). (C,G)
Ror2 exhibits a gradient expression, with higher level in the
anterior palate (C) and lower in the posterior region (G). (D,H)
Gradient Catnb expression is detected in the developing palate,
higher in the anterior (D), while lower in the posterior (H) palate. There is
strong Catnb expression in the MEE (arrow) of the anterior palate. T,
tongue; PS, palatal shelf.