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Figure 2


Fig. 2. Pcdh-{gamma} proteins localize to retinal plexiform layers during postnatal development. (A-D) Immunolabeling of Pcdh-{gamma} fusg/fusg retina at P0 (A), P3 (B), P7 (C) and P14 (D) with GFP antibody. At P0 (A) and P3 (B), Pcdh-{gamma}-GFP proteins are present in the IPL and retinal axon layer (arrow), and are distributed around cell somata in the neuroblast layer (NBL; other abbreviations as in Fig. 1). At P3, Pcdh-{gamma} proteins are also present in presumptive horizontal cells (asterisk; inset in B). (C) By P7, Pcdh-{gamma}-GFPs are detected in the emerging OPL, as it develops between the ONL and INL. (D) By P14, the adult pattern of Pcdh-{gamma}-GFP localization (see Fig. 1) is attained. Scale bars: 20 µm in A; 10 µm in inset.





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