|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 4. Dll and dac expression in the absence of Dpp signaling
and brk. (A-A'') Mitotic clones mutant for
brk (arrow; marked by the absence of GFP, green, and outlined in red
in A'') and tkv [arrow; marked by the absence of
arm-lacZ (red) and outlined in yellow in A''] derepress
Dll. These clones were induced separately and therefore result in
independent clonal events. Cells mutant for both genes show no GFP (green) and
no β-gal staining (red) (A'). (A'') Dll is
derepressed cell autonomously throughout the brk- clone
(marked by the red line), including cells that are also
tkv- (marked by the yellow line). (B-B'')
Cross-section of the same disc in A showing that the brk-;
tkv- clone is proximal to the Dll expression domain
(arrow, outlined in yellow). (B'') Schematic representation of the
cross-section shown in B. Dll expression is shown in gray and the
yellow arrow marks the region where Dll is derepressed (dark gray).
tr, trocanter. (C-C'') A proximal clone doubly mutant for
brk (absence of GFP, green) and tkv (absence of
arm-lacZ, green) showing derepression of Dll (arrowhead,
red) and dac (arrow, blue). These clones were induced at the same
time, and are therefore congruent. (D-D') Cross-section of the
same disc as in C showing that the brk-;tkv-
clone (outlined in yellow) is proximal to the Dll and dac
expression domains.
|
