spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 4


Fig. 4. Function of Ad4BP/SF-1 in the gonadal cortex before sexual differentiation. (A-E) Chick embryonic fibroblasts producing Ad4BP/SF-1 (A,B,D) and AP (C,E)-encoding viruses were implanted into the right presumptive gonad of both sexes at stage 11-12. The distribution of Ad4BP/SF-1-encoding viruses was examined by in situ hybridization for chick Ad4BP/SF-1 (A). As chick Ad4BP/SF-1 was used for the implantation study, in situ hybridization detected both endogenous and exogenous expression. The arrowhead in A indicates viral distribution in the developing right gonadal cortex, where Ad4BP/SF-1 gene is not endogenously activated (see Fig. 1K). The effects on cell proliferation (B,C) and cortical thickness (D,E) were examined as described in Fig. 3. (F,G) Relative numbers of BrdU-positive cells in the cortex (F) and medulla (G). Scale bars: 100 µm in A-C; 50 µm in D,E.





Right arrow Return to article