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Figure 7


Fig. 7. Proposed model for the specification of fates in the R1/R6/R7 equivalence group. Because N is not activated in the R1 and R6 precursors, they express Svp, which prevents expression of Sal (and likely other determinants of R7 and R8 fate), resulting in adoption of the default R1/R6 fate. By contrast, Dl in R1 and R6 activates N in the R7 precursor. N represses svp, allowing expression of Sal (and other determinants of R7 and R8 fate), which promotes both R7 and R8 fates; mutual negative feedback between the two programs would result in stochastic adoption of either the R7 or the R8 fate, but, in parallel, N represses sens, resulting in exclusive adoption of the R7 fate. See text for details.





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