|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 1. meis1 retracts accompanying the ath5 wave and becomes
restricted to the CMZ. (A-D) meis1 and (E-H)
ath5 expression analyzed by single in situ hybridization.
Developmental stages are indicated as hours post-fertilization (hpf) at
28.5°C. Lateral views of whole-mount (A,E) or dissected (B-D,F-H) eyes,
with dorsal up and anterior to the left. The front of the ath5 domain
is marked by black arrowheads. The red arrowhead in D points to meis1
expression in the prospective ciliary margin. (I-M) Transverse 40 µm
vibratome sections. (I,J) Dorsal is up. meis1 is weakly expressed in
the lens ectoderm before its thickening (I), but no signal is detected once
the lens placode is formed (J). (K-M) Dorsal is to the left. meis1
and ath5 expression domains are complementary as shown by double in
situ hybridization (K,L). Approximate limits of the ath5 signal are
indicated by the black arrowheads. (M) At 42hpf, meis1 expression is
detected by in situ hybridization in the ciliary margin (red arrowheads) and
in the postmitotic ganglion cells (black arrowhead). L, lens.
|
