spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 4


Fig. 4. Clonal overerexpression of meis1 in the developing eye prevents differentiation and results in cell sorting. Single optical sections from confocal z-stacks of GFP (A-C) or GFP-Meis1 (D-F) expressing clones induced genetically in developing eyes. GFP-meis1 signal is nuclear. At 24-30hpf, both clone types frequently span the whole width of the neuroepithelium (A,D). Confocal optical sections through the central retina (B,E) and z-sections (C,F) of 48hpf eyes. At this stage, GFP clones comprise both Islet1-expressing and non-expressing cells (B,C). By contrast, same-stage GFP-Meis1 clones in the central retina do not contain Islet1-positive cells (E). GFP-Meis1 clones are often located in the CMZ (F). The arrowheads (C,F) point to the CMZ, and the retina and the lens (L) are outlined.





Right arrow Return to article