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Fig. 5. Maternal expression of Groucho or its derivatives does not disrupt embryonic anteroposterior axis formation. The anterior localisation of hb (A-D) and posterior localisation of nos (E-H) RNA transcripts, as well as the degradation of the Cic protein at the termini (I-L) are indistinguishable in early stage 5 control embryos (A,E,I) and in embryos maternally expressing Gro (B,F,J) or its variants, Gro^AA (C,G,K) and Gro^DD (D,H,L). By contrast, the posterior zygotic hb stripe is derepressed posteriorly in Gro (B) and Gro^AA (C), but not in Gro^DD (D)-expressing embryos. hb is not derepressed in a ventroposterior domain in Gro (B) and Gro^AA (C) expressing embryos (white arrows), in accordance with the enduring hkb expression in these embryos (see Fig. 4F,G). (A-D,I-L) Black arrows indicate the same relative positions in all embryos.

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