spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 2


Fig. 2. Organisation of the mib2 locus and the Mib2 protein. (A) The Drosophila mib2 locus, as summarised by the BDGP and our sequence analysis of mib2 alleles and cDNA. The horizontal line represents genomic DNA; the white boxes represent genes mapping in the 37B region; the green boxes represent exons of mib2. Positions of P-element insertion in mib2KG10508 (red arrowhead), nonsense codon in mib21 (red arrow) and mib2r14 deletion (bracket) are indicated. Below the cDNA, coloured lines indicate the extent of Mib2 domains. Modular organisation of Mib2 protein (1049 amino acids) and comparison with Mib1 and SKE. The red line represents the region of mib2 sequence used to make the RNAi construct. (B) Alignment of ankyrin (framed in orange) and RING (framed in blue) domains of Mib2, SKE and Mib1 proteins. Percentage identity between Mib2 and SKE or MIb1 is shown in the column on the right. Consensus sequence for the RING-finger motif is indicated below the blue box.





Right arrow Return to article