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Figure 3


Fig. 3. Early somitogenesis is perturbed in Lfng{Delta}FCE1/{Delta}FCE1 embryos. Parasagittal sections of Lfng+/{Delta}FCE1 and Lfng{Delta}FCE1/{Delta}FCE1 embryos at 9.5 dpc (A,B) and 10.5 dpc (C-F). At 9.5 dpc, recently formed somites are irregularly sized and shaped in Lfng{Delta}FCE1/{Delta}FCE1 embryos (bracket, B). At 10.5 dpc, mature somites in the thoracic region remain irregular in Lfng{Delta}FCE1/{Delta}FCE1 embryos with fused (arrow), small (*) and large (bracket) somites seen (D). At this stage, however, the recently formed somites appear relatively normal in wild-type and Lfng{Delta}FCE1/{Delta}FCE1 embryos (E,F; lines represent intersomitic boundaries). Anterior is towards the left.





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