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Figure 5


Fig. 5. Analysis of division orientation. Analysis of division orientation at the fourth and fifth cleavage divisions. (A) Percentage of asymmetric and symmetric divisions in fourth and fifth cleavage (average±s.e.m.). (B) Analysis of cell division orientations of the two daughters of an asymmetric (A) or symmetric (S) division in the fourth cleavage round. The possible permutations (shown) differ significantly depending on the orientation of the fourth cleavage ({chi}2 test, P<0.001). `I' denotes a division where both daughters lie inside the embryo. (C,D) Proportion of asymmetric/symmetric divisions of the 4-cell-stage descendants at fourth and fifth cleavage (average±s.e.m.) for the four classes. (C) ME and EM embryos; (D) MM and EE embryos. Each pair of columns represents the descendants of one of the 4-cell blastomeres (see legend of Fig. 2 for abbreviations).





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