|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 1. Embryonic dorsoventral patterning is unaffected by the absence of HSPG
synthesis. (A-E) Dark-field images of cuticles from (A) wild-type
and (B-E) mutant larvae. (F-H) Dorsal and lateral views of eggs laid by
wild-type and ttv mothers. Anterior is to the left. (A) The ventral
cuticle of wild-type larvae displays a regular segmental pattern of denticle
belts alternating with bands of naked cuticle. (B) Larvae mutant for
hh (as well as wg) develop a continuous lawn of denticles
due to loss of naked cuticle. (C) sfl germline clone (glc) larvae
lacking maternal and zygotic N-deacetyl/N-sulfotransferase activity show loss
of naked cuticle and fused denticles resembling the hh mutant
phenotype, but no increase in denticle belt width or DV patterning defects.
(D) ttv glc larvae display a similar phenotype, with no abnormalities
in DV patterning. (E) The phenotype of a ttv mutant larva from a
depleted mother that lacks somatic and germline ttv activity
resembles ttv glc mutants. (F) Paired paddle-shaped dorsal appendages
are located posterior to the operculum (line) at the anterior of the wild-type
eggshell. (G) Eggshell morphology is unaffected by loss of ttv
activity in the germline. (H) Eggs laid by Ttv-depleted females are shorter
and have a smaller operculum (black bar), phenotypes associated with reduced
Dpp signaling activity in follicle cells.
|
