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Fig. 4. Rspo2 and Lrp6 interact during morphogenesis of the limbs. Alcian
Blue and Alizarin Red stained E18.5 right forelimbs (A-F) and left
hindlimbs (G-L). Asterisks in A-D and G-J indicate absence of digits.
Arrowheads in A and C indicate absence of a radius. Arrow in C indicates
malformation of the humerus. Arrowhead in G-I indicate absence of the fibula.
Arrow in I indicates absence of the femur.