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Figure 3


Fig. 3. Fat and Hippo signaling regulate the nuclear localization of Yki. (A-H') High magnification views of imaginal discs, stained for Yki (red), nuclei (DAPI, blue) and containing mutant clones marked by absence of GFP (green). (A) wtsX1, (B) Mer4; exe1, (C) fatG-rv, (D) exe1, (E) exe1 fatG-rv, (F) hpo42-47, (G) matse235 and (H) fatG-rv. Arrows indicate clone edges. (I-J') High magnification views of imaginal discs expressing RNAi lines under ci-Gal4 control, stained for Yki (red), nuclei (DAPI, blue) and Engrailed (green). ci-Gal4 drives expression in anterior cells (yellow line), partially complementary to Engrailed. (I) ci-Gal4 UAS-ex RNAi UAS-dcr2. (J) ci-Gal4 UAS-fat RNAi UAS-dcr2.





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