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Fig. 7. Essential role of Src-induced Arm/TCF activity in tracheal cell adhesion. (A-F) Time-lapse observations of btl>GFP-moesin (A-D,F) or btl> ${alpha}$ Cat-GFP (E) in control (B), btl>TCF ${Delta}$ N (C), btl>Src42A^ACT (A,D), btl>Src42A^ACT; shg^IH (E) and btl>Src42A^ACT, TCF ${Delta}$ N (F) embryos. (A) Metastasis-like behavior of tracheal cells expressing Src42A^ACT. Cells numbered 1 and 2 detached from one branch and reattached to an adjacent branch. (B-E) Src42A^ACT and TCF ${Delta}$ N synergistically caused a strong cell dissociation phenotype. Asterisk in E indicates the autofluorescence of yolk. Original movies for A,B,D and F are presented as Movies 8, 9 in the supplementary material. (G) Model of the dual function of Src42A on E-cadherin. Scale bar in B: 50 µm for B-D,F; 25 µm for E; 10 µm for A.

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