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Figure 6


Fig. 6. Compensatory increase of Myod1 expression in Myf5-Cre//DTA embryos. (A-F) In situ hybridization of Myf5-Cre//DTA (A-C) and wild-type (D-F) embryos at E10.5 (A,D), E11.5 (B,E) and E12.5 (C,F) with a probes against Myod1. No expression of Myod1 was observed in Myf5-Cre//DTA embryos at E10.5. At E11.5 an abnormal expression of Myod1 was present in the hypaxial part of the dermomyotome of Myf5-Cre//DTA embryos compared with the more widespread expression in wild-type embryos. At E12.5, no major differences in the expression of Myod1 were found between wild-type and mutant embryos. Scale bars: 150 µm.





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