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Figure 1


Fig. 1. Diversity of fibrocytes in the cochlea and structure of the stria vascularis. (A) Illustration of the distribution of subtypes of otic fibrocytes on a midmodiolar cochlea section. Subtypes are as indicated in the figure. Based on location, cell morphology and marker gene expression, five major types of fibrocytes can be distinguished in the spiral ligament. (B) Scheme of the cellular structure of the stria vascularis. Cell types are as indicated in the figure. Stria vascularis integrity relies on a three-layered tissue architecture of marginal, intermediate and basal cells that enclose a dense capillary network. The formation of long cell processes by all three cell types and a high degree of interdigitation characterizes strial architecture. OC, Organ of Corti; OtC, otic capsule; SL, spiral ligament; SLB, spiral limbus; StV, stria vascularis.





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