|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 6. Defects in the stria vascularis of Tbx18KO mice.
(A-L) Detection of strial proteins by immunofluorescence on midmodiolar
sections of cochleae of control and Tbx18KO mice at P21. Figures show
the stria vascularis in the basal turn. Antibodies against proteins of
marginal, intermediate and basal cells, as well as of basement membrane
components, were used as indicated in the figure. (C-F) Immunofluorescence on
DAPI-counterstained sections detected by laser scanning microscopy. Insets
show higher magnifications of the stria vascularis at regions indicated by
rectangles in the figures, and reveal the disturbed formation of cellular
processes by marginal cells (C,D) and intermediate cells (E,F). (M)
Schematic summary of expression domains and model of the stria vascularis of
wild-type and Tbx18KO mice.
|
