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Figure 5


Fig. 5. Wnt signaling promotes the generation of neural crest cells by inducing Bmp4 expression. Relative Bmp4 and Sp5 mRNA levels measured by quantitative real-time PCR in stage 2 M chick explants cultured in the absence (M) or presence (M+Wnt3A) of Wnt3A, or in stage 2 B explants cultured in the absence (B) or presence (B+Frz) of mFrz8CRD. Bars represent mean ± s.e.m. of five independent experiments. *P<0.05, **P<0.01; two-sided, one-sample t-test.





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